Table 3.
Summary of traditional risk factors, by study
Ref.
|
Advancing age (years)
|
MELD-Na
|
Portal vein pressure (mmHg)
|
QTc (millisecond)
|
IHD (previous history)
|
CVA/TIA (previous history)
|
Modha et al[45] | 63.6 vs 57.1 (P = 0.041)1 | > 25, P = 0.018 | ||||
Nguyen et al[47] | 21 vs 17, P = 0.037; [HR = 1.08 (1.02-1.14), P = 0.014] | HR = 3.48 (1.53-7.88), P = 0.002 | HR = 4.45 (1.52-12.98), P = 0.006 | |||
Vanderschueren et al[41] | 61.5 vs 67 [HR = 1.05 (1.01-1.09), P = 0.013] | |||||
Venner et al[46] | 64.3 vs 57.4 [OR = 1.02 (1.01-1.03), P = 0.006] | 453 vs 431 [OR = 1.03 (1.00-1.01), P = 0.01] | ||||
Wade et al[48] | 13.5 vs 17.1 (P = 0.007) |
Mean age (standard deviation), all other values for age are median (interquartile range).
MELD-Na: Model for end-stage liver disease incorporating serum sodium; QTc: Corrected QT interval (> 440 milliseconds considered prolonged); IHD: Ischaemic heart disease; CVA/TIA: Cerebrovascular accident/transient ischaemic attack; HR: Hazard ratio; OR: Odds ratio.