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. 2025 Jul 21;31(27):107740. doi: 10.3748/wjg.v31.i27.107740

Table 3.

Summary of traditional risk factors, by study

Ref.
Advancing age (years)
MELD-Na
Portal vein pressure (mmHg)
QTc (millisecond)
IHD (previous history)
CVA/TIA (previous history)
Modha et al[45] 63.6 vs 57.1 (P = 0.041)1 > 25, P = 0.018
Nguyen et al[47] 21 vs 17, P = 0.037; [HR = 1.08 (1.02-1.14), P = 0.014] HR = 3.48 (1.53-7.88), P = 0.002 HR = 4.45 (1.52-12.98), P = 0.006
Vanderschueren et al[41] 61.5 vs 67 [HR = 1.05 (1.01-1.09), P = 0.013]
Venner et al[46] 64.3 vs 57.4 [OR = 1.02 (1.01-1.03), P = 0.006] 453 vs 431 [OR = 1.03 (1.00-1.01), P = 0.01]
Wade et al[48] 13.5 vs 17.1 (P = 0.007)
1

Mean age (standard deviation), all other values for age are median (interquartile range).

MELD-Na: Model for end-stage liver disease incorporating serum sodium; QTc: Corrected QT interval (> 440 milliseconds considered prolonged); IHD: Ischaemic heart disease; CVA/TIA: Cerebrovascular accident/transient ischaemic attack; HR: Hazard ratio; OR: Odds ratio.