Table 3. Comparison of Laboratory Findings between Patients with Single-organ and Multi-organ Involvement .
| Items |
Single-organ Involvement
( n =35) |
Multi-organ Involvement
( n =47) |
P Value |
| Red blood cells ( × 1012/L) | 4.20 (3.79 – 4.51) | 3.96 (3.59 – 4.39) | 0.391 |
| Platelets ( × 109/L) | 195.00 (135.00 – 248.00) | 208.00 (151.00 – 281.00) | 0.536 |
| Hemoglobin (g/L) | 122.63 ± 26.88 | 118.94 ± 18.70 | 0.465 |
| White blood cells ( × 109/L) | 5.76 (4.27 – 8.37) | 6.33 (4.61 – 7.47) | 0.959 |
| Neutrophil percentage (%) | 66.96 ± 13.09 | 62.30 ± 12.33 | 0.103 |
| Absolute neutrophil count ( × 109/L) | 3.82 (2.63 – 6.76) | 3.52 (2.89 – 4.91) | 0.574 |
| Basophil percentage (%) | 0.40 (0.10 – 0.60) | 0.50 (0.20 – 0.80) | 0.200 |
| Absolute basophil count ( × 109/L) | 0.02 (0.01 – 0.03) | 0.03 (0.02 – 0.04) | 0.098 |
| Eosinophil percentage (%) | 1.80 (0.40 – 3.50) | 3.30 (1.70 – 6.90) | 0.010* |
| Absolute eosinophil count ( × 109/L) | 0.09 (0.04 – 0.19) | 0.20 (0.11 – 0.37) | 0.006* |
| Lymphocyte percentage (%) | 21.42 ± 8.96 | 22.97 ± 7.63 | 0.401 |
| Absolute lymphocyte count ( × 109/L) | 1.17 (0.96 – 1.46) | 1.28 (1.02 – 1.73) | 0.259 |
| Monocyte percentage (%) | 8.20 (6.50 – 10.10) | 8.20 (7.20 – 10.30) | 0.442 |
| Absolute monocyte count ( × 109/L) | 0.47 (0.30 – 0.63) | 0.53 (0.43 – 0.68) | 0.356 |
| Serum IgG4 levels (n, %)a | n=30 | n=37 | |
| IgG4 ≤ ULN | 6 (20.00%) | 5 (13.51%) | 0.068 |
| ULN < IgG4 < 2 × ULN | 9 (30.00%) | 9 (24.32%) | |
| 2 × ULN ≤ IgG4 < 5 × ULN | 13 (43.33%) | 11 (29.73%) | |
| IgG4 ≥ 5 × ULN | 2 (6.67%) | 12 (32.43%) | |
| IgG (g/L)b | 16.69 (12.60 – 23.58) | 20.40 (16.85 – 27.40) | 0.046* |
| C3 (g/L)c | 0.98 ± 0.31 | 1.02 ± 0.37 | 0.640 |
| C4 (g/L)d | 0.22 ± 0.12 | 0.22 ± 0.13 | 0.796 |
| ESR (mm/h)e | 40.00 (14.00–78.00) | 79.50 (40.25–120.00) | 0.002* |
| CRP (mg/L)f | 8.11 (2.19–37.32) | 7.06 (3.22–22.96) | 0.804 |
ULN, Upper limit of normal; IgG4, Immunoglobulin G4; IgG, Immunoglobulin G; C3, Complement C3; C4, Complement C4; ESR, Erythrocyte sedimentation rate; CRP, C-reactive protein.
Date are n (%), mean ± SD, or median (IQR), unless otherwise indicated.
* Values indicate statistical significance.
aA total of 67 patients underwent serum IgG4 testing.
bA total of 64 patients underwent serum IgG testing.
cA total of 63 patients underwent C3 testing.
dA total of 63 patients underwent C4 testing.
eA total of 63 patients underwent ESR testing.
fA total of 77 patients underwent CRP testing.