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. 2025 Jul 9;68(14):14195–14222. doi: 10.1021/acs.jmedchem.5c00781

2. Evolution of the Neutral Series.

graphic file with name jm5c00781_0017.jpg

a

Inhibition of nigericin-triggered speck formation.

b

logD measured as partitioning between water and octanol at pH 7.4.

c

HLM: human liver microsomes, μL/min/mg.

d

HHeps: human hepatocytes, μL/min/106 cells.

e

RHeps: rat hepatocytes, μL/min/106 cells.