1. Reaction Optimization for Enantioselective Synthesis.
Yields were not quantified due to volatility of the products.
Enantiomeric ratio was measured by chiral HPLC of the p-nitrobenzoate ester derivative of the products. See Supporting Information.
Products were formed with >20:1 diastereomeric ratio based on 1H NMR analysis of the crude reaction mixtures.
