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Mutual information profiles for ZDV (a), ddC (b), ddI (c), d4T (d), 3TC (e), ABC (f), NVP (g), DLV (h), EFV (i), SQV (j), IDV (k), RTV (l), NFV (m), and APV (n). In a–i, position 0 denotes the insertion flag, 1–250 represent the first 250 positions of the HIV-1 reverse transcriptase; in j–n, positions 1–99 of the HIV-1 protease are displayed. Peaks above 0.06 bits are annotated for ddC, ddI, and d4T, and peaks above 0.1 bits are annotated for all other drugs.
