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. 2025 Jul 28;18:121. doi: 10.1186/s12920-025-02189-2

Table 3.

Accelerated epigenetic aging in newborns with CHD and by specific diagnostic subgroup

N PedBE age days, mean sd Chronological DOL, mean sd EAA days, mean sd p
CTL 26 43.3 32.2 29.3 11.0 13.9 29.8 -
CHD, all 33 83.5 76.6 10.6 17.0 72.9 76.7 0.0005
SV 14 67.6 48.6 10.9 13.5 56.6 48.4 0.0013
2V 10 83.3 49.1 18.5 42.9 64.8 42.9 0.0003
2V TGA 9 108.5 125.5 1.2 0.4 107.2 125.6 0.0010

P-values: t-test between all CHD cases and subgroups with controls