Table 3.
Correlation Coefficients (p-value) Between QCT Measurements and Lung Function Measurements in Emphysema Group
| FEV1 | FVC | FEV1/FVC | FEV1%Predicted | |
|---|---|---|---|---|
| EI of right upper lobe | 0.092 (0.366) | 0.075 (0.458) | 0.032 (0.756) | 0.197 (0.051) |
| EI of right middle lobe | 0.053 (0.601) | 0.046 (0.649) | 0.001 (0.994) | 0.181 (0.074) |
| EI of right lower lobe | 0.076 (0.455) | 0.065 (0.525) | −0.002 (0.988) | 0.104 (0.307) |
| EI of right lung | 0.077 (0.449) | 0.063 (0.533) | 0.015 (0.887) | 0.149 (0.142) |
| EI of left upper lobe | 0.102 (0.313) | 0.090 (0.374) | 0.011 (0.916) | 0.169 (0.095) |
| EI of left lower lobe | 0.100 (0.326) | 0.092 (0.366) | −0.007 (0.948) | 0.108 (0.285) |
| EI of left lung | 0.092 (0.363) | 0.082 (0.420) | 0.002 (0.988) | 0.132 (0.194) |
| Overall lung | 0.083 (0.412) | 0.073 (0.471) | 0.001 (0.993) | 0.142 (0.161) |
| Perc15 | −0.135 (0.181) | −0.131 (0.197) | 0.018 (0.858) | −0.168 (0.096) |
| MLD of overall lung, HU | −0.242 (0.016) | −0.269 (0.007) | 0.105 (0.303) | −0.209 (0.038) |
| MLD of right upper lobe, HU | −0.177 (0.080) | −0.211 (0.036) | 0.117 (0.250) | −0.230 (0.022) |
| MLD of right middle lobe, HU | −0.166 (0.101) | −0.210 (0.037) | 0.155 (0.126) | −0.185 (0.067) |
| MLD of right lower lobe, HU | −0.219 (0.030) | −0.236 (0.019) | 0.078 (0.441) | −0.190 (0.060) |
| MLD of left upper lobe, HU | −0.275 (0.006) | −0.307 (0.002) | 0.117 (0.250) | −0.186 (0.065) |
| MLD of left lower lobe, HU | −0.241 (0.016) | −0.261 (0.009) | 0.064 (0.529) | −0.221 (0.028) |
| Pi10, mm | −0.044 (0.669) | −0.052 (0.612) | 0.031 (0.764) | −0.067 (0.509) |
| WA% | −0.121 (0.231) | −0.156 (0.124) | 0.133 (0.190) | −0.046 (0.650) |
| WT, mm | 0.017 (0.870) | 0.010 (0.922) | 0.067 (0.507) | −0.128 (0.208) |
| Surface area, mm2 | 0.494 (<0.001) | 0.507 (<0.001) | −0.091 (0.371) | 0.135 (0.181) |
| TBV, mm3 | 0.486 (<0.001) | 0.505 (<0.001) | −0.095 (0.350) | 0.137 (0.178) |
| BV5, mm3 | 0.473 (<0.001) | 0.481 (<0.001) | −0.087 (0.394) | 0.139 (0.169) |
| BV5/TBV | −0.251 (0.012) | −0.283 (0.005) | 0.082 (0.418) | −0.012 (0.904) |
Notes: a. Bold text indicates statistically significant results (p < 0.05).
Abbreviations: FEV1, Forced Expiratory Volume in 1 second; FVC, Forced Vital Capacity; Perc15, The 15th percentile of lung; density MLD, Mean Lung Density, measured in Hounsfield Units (HU); Pi10, Square root of the wall area for a hypothetical airway with an internal perimeter of 10 mm; WA%, Airway Wall Area Percentage; WT, Airway Wall Thickness; Surface Area, Total surface area of the lungs; TBV, Total Blood Volume; BV5, Blood Volume in vessels smaller than 5 mm³; BV5/TBV, Ratio of blood volume in vessels smaller than 5 mm³ to Total Blood Volume.