Table 2.
Baseline bacterial characteristics of CRKp isolated from each patient at unique admissions.
| Characteristics; n (%) | Total (n = 630) | Linked admission (n = 404) | Out of network (n = 226) | P value |
|---|---|---|---|---|
| Culture source | – | |||
| Blood | 102 (16) | 55 (14) | 47 (21) | |
| Respiratory | 92 (15) | 65 (16) | 27 (12) | |
| Urine | 341 (54) | 219 (54) | 122 (54) | |
| Wound | 59 (9.4) | 42 (10) | 17 (7.5) | |
| Other | 36 (5.7) | 23 (5.7) | 13 (5.8) | |
| Multi-locus sequence type (MLST) | < 0.001 | |||
| 258 | 495 (79) | 353 (87) | 142 (63) | |
| 11 | 28 (4.4) | 19 (4.7) | 9 (4.0) | |
| 307 | 34 (5.4) | 17 (4.2) | 17 (7.5) | |
| 37 | 8 (1.3) | 3 (0.7) | 5 (2.2) | |
Other ( 5 isolates per ST)a
|
65 (10) | 12 (3.0) | 53 (24) | |
| wzi type | < 0.001 | |||
| 154 | 322 (51) | 225 (56) | 97 (43) | |
| 173 | 36 (5.7) | 17 (4.2) | 19 (8.4) | |
| 29 | 175 (28) | 129 (32) | 46 (20) | |
| 27 | 29 (4.6) | 19 (4.7) | 10 (4.4) | |
Other ( 5 isolates per type)b
|
68 (11) | 14 (3.5) | 54 (24) | |
| bla carbapenemase | ||||
| KPC-2 | 281 (45) | 175 (43) | 106 (47) | – |
| KPC-3 | 332 (53) | 225 (56) | 107 (47) | 0.046 |
| NDM-1 | 5 (0.8) | 2 (0.5) | 3 (1.3) | – |
| NDM-5 | 2 (0.3) | 0 (0) | 2 (0.9) | – |
| OXA-181 | 1 (0.2) | 0 (0) | 1 (0.4) | – |
| OXA-48 | 2 (0.3) | 0 (0) | 2 (0.9) | – |
| OXA-232 | 26 (4.1) | 16 (4.0) | 10 (4.4) | – |
| bla extended spectrum β-lactamase | ||||
| SHV-12 | 244 (39) | 176 (44) | 68 (30) | < 0.001 |
| SHV-28 | 38 (6.0) | 16 (4.0) | 22 (9.7) | 0.005 |
| SHV-7 | 3 (0.5) | 0 (0) | 3 (1.3) | 0.046 |
| CTX-M-14 | 4 (0.6) | 2 (0.5) | 2 (0.9) | – |
| CTX-M-15 | 100 (16) | 53 (13) | 47 (21) | 0.013 |
aMLST (n): 1084 (1), 1140 (1), 1228 (1), 133 (1), 14 (3), 147 (2), 1496 (1), 15 (3), 16 (1), 17 (1), 188 (1), 20 (2), 2167 (1), 22 (1), 231 (5), 247 (1), 26 (1), 2623 (1), 2891 (1), 299 (1), 336 (1), 34 (1), 340 (2), 3520 (1), 36 (1), 3631 (1), 38 (1), 3807 (1), 3878 (1), 39 (1), 3925 (1), 395 (2), 418 (4), 45 (5), 461 (1), 48 (2), 54 (1), 656 (1), 76 (2), 792 (1), 846 (1), 941 (1), 985 (1), non-typeable (1).
bwzi type (n): 100 (3), 101 (4), 104 (5), 105 (1), 108 (1), 114 (2), 14 (2), 141 (1), 149 (2), 16 (1), 167 (2), 17 (1), 177 (2), 18 (1), 180 (1), 193 (1), 199 (2), 2 (2), 21 (1), 23 (1), 25 (1), 31 (3), 39 (2), 5 (1), 50 (4), 54 (1), 64 (2), 7 (1), 83 (2), 84 (2), 9 (1), 93 (3), 96 (7), non-typeable (2).