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. 2025 Apr 8;23(10):1137–1155. doi: 10.2174/1570159X23666250326091016

Table 4.

In vitro inhibition of BuChE and AChE by compounds isolated from Buxus natalensis.

Phytoconstituent Structure IC50 (µM) BuChE IC50 (µM) AChE Selectivitya References
Buxafuranamide graphic file with name CN-23-10-1137-t4-1.jpg N.D. 14.0 - [44]
Buxalongifolamide graphic file with name CN-23-10-1137-t4-2.jpg N.D. 30.2 - [44]
Buxamine A graphic file with name CN-23-10-1137-t4-3.jpg N.D. 80.0 - [44]
Buxaminol A graphic file with name CN-23-10-1137-t4-4.jpg N.D. 29.8 - [44]
Buxaminol C graphic file with name CN-23-10-1137-t4-5.jpg N.D. 40.4 - [44]
Cyclobuxophylline graphic file with name CN-23-10-1137-t4-6.jpg N.D. 58.2 - [44]
Cyclonataminol graphic file with name CN-23-10-1137-t4-7.jpg N.D. 22.9 - [44]
31-Demethylbuxaminol A graphic file with name CN-23-10-1137-t4-8.jpg N.D. 25.8 - [44]
O2-Natafuranamine graphic file with name CN-23-10-1137-t4-9.jpg N.D. 3.0 - [44]
O10-Natafuranamine graphic file with name CN-23-10-1137-t4-10.jpg N.D. 8.5 - [44]

Note: aSelectivity = IC50 BuChE/IC50 AChE.