Table 6.

In vitro inhibition of BuChE and AChE by compounds isolated from Sarcococca hookeriana ‡ and Sarcococca coriacea ‡‡.

Phytoconstituent	Structures	IC50 (µM) BuChE	IC50 (µM) AChE	Selectivitya	References
Dictyophlebine ‡		3.6	6.2	1.72	[52]
Sarcovagenine C ‡		0.7 0.3	1.5 8.0	2.14 26.7	[31, 52]
Epoxynepapakistanine A ‡‡		77.4	>200	>2.58	[51]
Funtumarine C ‡‡		6.56	45.75	6.97	[51]
Hookerrianamide D ‡		100.2	59.0	58.9	[31]
Hookerrianamide E ‡		6.0	15.9	2.65	[31]
Hookerrianamide F ‡		7.2	1.6	0.22	[31]
Hookerrianamide G ‡		1.5	11.4	7.6	[31]
Hookerrianamide H ‡		1.9	2.9	1.53	[52]
Hookerrianamide I ‡		0.3	34.1	113.7	[52]
Nα-Methylepipachysanine D ‡		3.2	10.1	3.16	[31]
N-Metylfuntumine ‡‡		12.69	97.61	7.69	[51]
Saligenamide A ‡		4.6	50.6	11.0	[31]
Sarcovagenine D ‡		2.3	2.2	0.96	[31]
Terminaline ‡		0.6	113.1	188.5	[31]

Note: ^aSelectivity = IC_{50 BuChE}/IC_{50 AChE.}