Table 1.
Pathological findings in 3 different tumor sites.
| Primary tumor | Lung nodule | Duodenal nodule | |
|---|---|---|---|
| Date of excision | 11/07/2021 | 01/06/2022 | 11/06/2023 |
|
| |||
| Histological type | Adenocarcinoma | Adenocarcinoma | Adenocarcinoma |
|
| |||
| Immunohistochemistry | MLH1 (+ve) MSH2 (+ve) MSH6 (+ve) PMS2 (+ve) |
CK7 (+) CK20 (−) CDX2 (+) ER (−) PR (−) PAX8 (−) TTF-1 (−) Napsin A (−) |
AE1/AE3 (+) CK7 (+) CD117 (−) CD34 (−) Chromogranin (−) Synaptophysin (−) CD56 (−) Ki67∼20% |
|
| |||
| Cytogenetic analysis (mutations) | KRASG12D NRAS wild-type BRCA2 SMAD4 APC p53 |
— | — |