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. 2025 Apr 28;122(1):185–195. doi: 10.1016/j.ajcnut.2025.04.022

TABLE 5.

Pooled effects of MMS compared with IFA on WLZ and wasting (fixed effects).

Effect of MMS vs. IFA WLZ score
Wasting (WLZ <−2)
No. of studies No. of infants Mean difference (95% CI), fixed effects No. of studies No. of infants Risk ratio (95% CI), fixed effects
Birth1 8 22,884 0.08 (0.05, 0.11) 8 21,567 0.90 (0.85, 0.96)
3 mo 7 24,688 0.03 (0.00, 0.06) 7 24,688 0.94 (0.85, 1.04)
6 mo 9 18,868 0.00 (−0.03, 0.04) 9 18,780 1.05 (0.94, 1.16)
12 mo 7 16,297 0.03 (−0.01, 0.07) 7 16,297 0.97 (0.90, 1.04)
18 mo 5 2922 0.06 (−0.02, 0.14) 5 2922 0.90 (0.72, 1.14)
24 mo 5 9810 −0.00 (−0.04, 0.04) 5 9810 1.01 (0.92, 1.09)

The table shows the generic inverse variance weighted pooled mean differences or pooled risk ratios with their corresponding 95% CI comparing MMS and IFA intervention groups. Number of infants were calculated from effective sample sizes.

Abbreviations: BMIZ, body mass index z-score; CI, confidence interval; IFA, iron and folic acid supplementation; MMS, multiple micronutrient supplementation; WLZ, weight-for-length z-score.

1

BMIZ for 5 studies and WLZ for 3 studies.