Table 5. . Proportion of days covered for PMO claims in the first year after index (n = 324).
| Adherence | Overall (n = 324) |
|---|---|
| Proportion of days covered (PDC), % Mean (SD) Median (IQR) Min, max |
66.9 (31.1) 78.8 (38.8, 94.0) 1.9, 100.0 |
| PDC category no. 1, n (%) Adherent (PDC ≥80%) Nonadherent (PDC <80%) |
161 (49.7) 163 (50.3) |
| PDC category no. 2, n (%) Very high adherence (PDC ≥90%) High adherence (PDC 80% to <90%) Moderate adherence (PDC 50% to <80%) Low adherence (PDC <50%) |
116 (35.8) 45 (13.9) 68 (21.0) 95 (29.3) |
The PDC is defined broadly as the proportion of days that an individual has access to medication during a specified observation period, based on the fill dates and days’ supply for each dispensing.
IQR: Interquartile range; PDC: Proportion of days covered; PMO: Phosphorodiamidate morpholino oligomer; SD: Standard deviation.