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. 2005 Oct;73(10):6562–6566. doi: 10.1128/IAI.73.10.6562-6566.2005

FIG. 1.

FIG. 1.

Effect of inactivating NADase on local tissue necrosis after subcutaneous inoculation with GAS. Each data point represents the area of skin necrosis surrounding the inoculation site on the indicated day after subcutaneous inoculation with GAS strain 771nga−slo+ (A) or GAS wild-type strain 771nga+slo+ (B). Mean lesion size is indicated by a cross. Data are from four independent experiments and a total of 40 mice for each challenge strain. P = 0.001 for comparison between strains.