Table 2.
Univariate analysis of poor prognosis at 3 months after acute ischemic stroke
| Statistics | Odds ratio (95% CI) | P-value | |
|---|---|---|---|
| Age, n (%) | |||
| < 60 | 435 (22.88%) | 1.0 | |
| 60 to < 70 | 505 (26.56%) | 1.15 (0.84, 1.58) | 0.3897 |
| 70 to < 80 | 668 (35.14%) | 1.89 (1.42, 2.52) | < 0.0001 |
| ≥ 80 | 293 (15.41%) | 3.93 (2.82, 5.47) | < 0.0001 |
| Gender, n (%) | |||
| Male | 1167 (61.39%) | 1.0 | |
| Female | 734 (38.61%) | 1.66 (1.36, 2.03) | < 0.0001 |
| BMI, mean (SD), kg/m2 | 23.50 ± 3.25 | 0.92 (0.89, 0.95) | < 0.0001 |
| WBC, mean (SD), 109/L | 8.14 ± 2.89 | 1.08 (1.04, 1.12) | < 0.0001 |
| RBC, mean (SD), 1012/L | 4.33 ± 0.64 | 0.59 (0.50, 0.69) | < 0.0001 |
| PLT, mean (SD), 109/L | 223.55 ± 71.31 | 1.00 (1.00, 1.00) | 0.2929 |
| ESR, median (min-max), mm/h | 0.00 (0.00-140.00) | 1.02 (1.01, 1.02) | < 0.0001 |
| TC, mean (SD), mg/dL | 179.43 ± 43.88 | 1.00 (0.99, 1.00) | 0.0002 |
| TG, mean (SD), mg/dL | 105.45 ± 60.00 | 1.00 (0.99, 1.00) | < 0.0001 |
| HDL, mean (SD), mg/dL | 44.15 ± 16.81 | 0.99 (0.99, 1.00) | 0.0295 |
| LDL, mean (SD), mg/dL | 104.29 ± 42.37 | 1.00 (0.99, 1.00) | 0.0014 |
| BUN, mean (SD), mg/dL | 17.59 ± 8.88 | 1.02 (1.01, 1.03) | 0.0037 |
| CR, median (min-max), mg/dL | 0.89 (0.36–13.91) | 1.01 (0.92, 1.11) | 0.7602 |
| ALB, mean (SD), g/dL | 4.02 ± 0.43 | 0.28 (0.22, 0.35) | < 0.0001 |
| HbA1c, mean (SD), % | 5.10 ± 2.75 | 1.01 (0.97, 1.04) | 0.6898 |
| hs-CRP, median (min-max), mg/dL | 0.12 (0.00-36.80) | 1.15 (1.11, 1.20) | < 0.0001 |
| INR, median (min-max) | 1.04 ± 0.33 | 1.43 (1.07, 1.92) | 0.0167 |
| APTT, median (min-max), s | 30.80 ± 6.51 | 0.99 (0.98, 1.01) | 0.2914 |
| Initial NIHSS score, median (min-max) | 3.00 (0.00–33.00) | 1.23 (1.20, 1.26) | < 0.0001 |
| Current smoking, n (%) | |||
| No | 1151 (60.55%) | 1.0 | |
| Yes | 750 (39.45%) | 0.61 (0.50, 0.75) | < 0.0001 |
| Previous stroke/TIA, n (%) | |||
| No | 1501 (78.96%) | 1.0 | |
| Yes | 400 (21.04%) | 1.81 (1.44, 2.29) | < 0.0001 |
| Hypertension, n (%) | |||
| No | 693 (36.45%) | 1.0 | |
| Yes | 1208 (63.55%) | 1.34 (1.09, 1.66) | 0.0063 |
| Diabetes, n (%) | |||
| No | 1289 (67.81%) | 1.0 | |
| Yes | 612 (32.19%) | 1.43 (1.16, 1.77) | 0.0007 |
| Hyperlipidemia, n (%) | |||
| No | 1203 (63.28%) | 1.0 | |
| Yes | 698 (36.72%) | 0.79 (0.64, 0.97) | 0.0245 |
| Atrial fibrillation, n (%) | |||
| No | 1497 (78.75%) | 1.0 | |
| Yes | 404 (21.25%) | 1.99 (1.58, 2.50) | <0.0001 |
| Coronary heart disease, n (%) | |||
| No | 1681 (88.43%) | 1.0 | |
| Yes | 220 (11.57%) | 1.03 (0.76, 1.40) | 0.8540 |
| Stroke etiology, n (%) | |||
| SVO | 607 (31.93%) | 1.0 | |
| LAA | 365 (19.20%) | 0.62 (0.45, 0.85) | 0.0031 |
| CE | 489 (25.72%) | 1.48 (1.14, 1.91) | 0.0029 |
| Other determined | 170 (8.94%) | 2.03 (1.43, 2.89) | < 0.0001 |
| Undetermined | 270 (14.20%) | 0.86 (0.61, 1.19) | 0.3598 |
| RDW, mean (SD), % | 13.36 ± 1.37 | 1.26 (1.17, 1.35) | < 0.0001 |