Table 3.

Data on histopathological accuracy

STUDY	TP	FP	FN	TN	Sensitivity (95% CI)	Specificity (95% CI)	PPV (95% CI)	NPV (95% CI)
Zikan (2010)[37]	116	1	1	0	0.991 (0.953 to 0.998)	0 (0 to 0.793)	0.991 (0.953 to 0.998)	0 (0 to 0.793)
Thabet (2014)[23]	7	0	0	1	1 (0.646 to 1)	1 (0.207 to 1)	1 (0.646 to 1)	1 (0.207 to 1)
Kong (2016)[29]	49	0	0	0	1 (0.927 to 1)	(NaN to NaN)	1 (0.927 to 1)	(NaN to NaN)
Epstein (2016)[28]	30	0	0	0	1 (0.886 to 1)	(NaN to NaN)	1 (0.886 to 1)	(NaN to NaN)
Yousefi (2017)[24]	8	0	0	0	1 (0.676 to 1)	(NaN to NaN)	1 (0.676 to 1)	(NaN to NaN)
Vlasak (2020)[21]	46	5	0	0	1 (0.923 to 1)	0 (0 to 0.434)	0.902 (0.79 to 0.957)	(NaN to NaN)
Verschuere (2021)[26]	35	1	3	4	0.921 (0.792 to 0.973)	0.8 (0.376 to 0.964)	0.972 (0.858 to 0.995)	0.571 (0.25 to 0.842)
Lengyel (2021)[31]	66	7	4	16	0.943 (0.862 to 0.978)	0.696 (0.491 to 0.844)	0.904 (0.815 to 0.953)	0.8 (0.584 to 0.919)
Buonomo (2022)[35]	16	1	0	0	1 (0.806 to 1)	0 (0 to 0.793)	0.941 (0.73 to 0.99)	(NaN to NaN)
Mascilini (2023)[30]	96	0	6	0	0.941 (0.878 to 0.973)	(NaN to NaN)	1 (0.962 to 1)	0 (0 to 0.39)

TP, true positive; FP, false positive; TN, true negative; FN, false negative; PPV, positive predictive value; NPV, negative predictive value; NaN, Not estimable due to zero values in denominator