FIG. 7.

Inhibitory capacity of PNAG and dPNAG in the opsonophagocytic assay against antisera raised to dPNAG-DT. Inhibition of opsonic killing of the staphylococcal strain indicated in each panel by rabbit serum raised to dPNAG-DT conjugate mixed with purified PNAG (solid bars) or dPNAG (open bars) antigens at the indicated concentration. Bars represent means of quadruplicate determinations, and error bars indicate the standard deviations. Inhibition of >40% is considered biologically significant and is statistically significant at P values of <0.01; ANOVA and Fisher PLSD posthoc, pairwise analysis.