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Protection against lethality caused by various S. aureus strains by a goat antiserum raised to the dPNAG-DT conjugate vaccine in comparison to NGS
| S. aureus strain | Challenge dose | No. of survivors/total (%)
|
P valuea | |
|---|---|---|---|---|
| NGS | dPNAG-DT serum | |||
| MN8 | 2 × 109 | 0/32 (0) | 29/32 (91) | <0.001 |
| 476 | 5 × 109 | 3/16 (18.7) | 11/16 (68.7) | 0.01 |
| 10833 | 5 × 109 | 2/16 (12.5) | 15/16 (94) | <.001 |
P value determined by chi-square analysis with continuity correction.
