(A) C. pneumoniae DNA positivity in lung tissue samples measured by nested PCR. (B) Lung inflammatory reactions measuring perivascular and peribronchial mononuclear cell infiltrates on a scale from 0 (no inflammation) to 4 (severe infiltration with occasional alveolar macrophages). Group I, six inoculations, starting at the age of 8 weeks; group II, three inoculations, starting at the age of 8 weeks; group III, three inoculations, starting at the age of 20 weeks; group IV, three inoculations, starting at the age of 20 weeks, and cholesterol feeding started at 18 weeks; group V, uninfected control. w, weeks.