TABLE 2.
Synopsis of comparative chromosomal deletions between A/HAR-13 and D/UW-3
| Deletion locationa | Deletion sizeb(bp) | Result |
|---|---|---|
| CT050 | 144 | In-frame deletion |
| CTA0122 (incD) | 13 | Frameshift; 30 bp added to ORF |
| CT154/CT155 | 453 | Truncates CTA0163 by 138 bp |
| Truncates CTA0164 by 3 bp | ||
| CT156/CT157 | 158 | Intergenic |
| CTA0175 | 22 | Frameshift; 57 bp added to ORF |
| CT166/CT167 | 946 | Toxin regionc |
| CT326 | 111 | In-frame deletion |
| CT414 (pmpC) | 42 | In-frame deletion |
| CTA0498 (Tarp) | 42 | In-frame deletion |
| CT456 (Tarp) | 345 | In-frame deletion |
| CT622 | 12 | In-frame deletion |
| CT662/CT663 | 7 | Integenic |
| CT680/CT681 | 8 | Intergenic |
| CTA0891/CTA0892 | 10 | Disrupts tyrP_2d homolog |
| CTA0917/CTA0918 | 7 | Intergenic |
| CTA0934 | 125 | Fuses two small ORFs in D, creating a single, larger ORF in A |
| CT869 (pmpE) | 12 | In-frame deletion |
| CTA0953 | 70 | Alters ORF annotation between strains |
a
CT numbers refer to D/UW-3-specific deletions and their relative locations, while CTA numbers refer to A/HAR-13 specific deletions and their relative locations. The ORFs flanking intergenic deletions are noted as well.
b
All deletions larger than 10 bp are listed, as well as any deletion less than 10 bp that is not a multiple of 3.
c
The annotated ORFs between the two strains are dramatically altered and have been previously reported (8).
d
tyrP-2, second copy of the tyrP gene (39).