TABLE 2.
Proportion of mice with positive blood cultures (≥ 2 CFU/ml) after infection under the indicated conditions with different strains of S. aureus
S. aureus strain and injection route | Time postinfection (h) | No. of mice with positive blood cultures/total no.
|
||
---|---|---|---|---|
WT | Complemented | Δica | ||
Newman, i.v. | 2 | 8/8 | 8/8 | 6/8 |
4 | 8/8 | 8/8 | 6/8 | |
10833, i.v. | 2 | 8/8 | 8/8 | 5/8 |
4 | 8/8 | 8/8 | 4/8a | |
MN8, i.v. | 2 | 8/8 | 8/8 | 3/8b |
4 | 8/8 | 8/8 | 1/8c | |
Newman, i.v./CSAd | 2 | NDe | 8/8 | 4/8a |
4 | ND | 8/8 | 3/8b | |
Newman, i.p. | 2 | ND | 8/8 | 4/8a |
4 | ND | 8/8 | 4/8a |
Significantly different from the value obtained for the WT strain (P = 0.038 by Fisher's exact test).
Significantly different from the value obtained for the WT strain (P = 0.013 by Fisher's exact test).
Significantly different from the value obtained for the WT strain (P = 0.0007 by Fisher's exact test).
CSA, Columbia salt agar used to prepare the inoculum.
ND, not done.