TABLE 5.
Antibody to | Category | Range | OR (CI), model 3 | P (test for trend) |
---|---|---|---|---|
16-kDa Ag | Low | ≤0.06 | 1.0 (Ref.) | <0.001 |
Medium | 0.07, 0.14 | 4.0 (1.9, 8.5) | ||
High | 0.15, 3.60 | 11.7 (4.9, 34.0) | ||
ESAT-6 | Low | ≤0.09 | 1.0 (Ref.) | 0.001 |
Medium | 0.09-0.2 | 1.9 (0.8, 4.1) | ||
High | 0.2-4.0 | 5.9 (2.0, 17.6) | ||
FdxA | Low | ≤0.11 | 1.0 (Ref.) | 0.016 |
Medium | 0.11-0.19 | 1.5 (0.7, 3.2) | ||
High | 0.19-1.95 | 2.8 (1.2, 6.4) |
ELISA results were trichotomized into the categories “low,” “medium,” and “high” according to the tertiles of the overall antibody distribution. Model 3 is based on backward elimination from antibodies found to be significant at an alpha of 0.003 (Table 3). OR, odds ratio; CI, confidence interval; Ref., reference range.