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. 2005 Oct;73(10):6229–6236. doi: 10.1128/IAI.73.10.6229-6236.2005

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Copyright © 2005, American Society for Microbiology

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FIG. 1. — Antibodies against prion protein (PrP^C) do not interfere with the intracellular behavior of B. suis. (A) Multiplication of B. suis in THP-1 human macrophages treated with antibodies against PrP^C. WT, without pretreatment; Ic, isotype antibody as control; SAF 32, 3F4, and 12F10, monoclonal antibodies used. (B) Multiplication of B. suis in the murine J774 macrophage cell line. WT, without pretreatment; Ic, isotype control; SAF 32 and SAF 61, monoclonal antibodies used. (B, insert) Multiplication of B. suis in murine J774 cells after incubation with a purified polyclonal antibody. Sc, control serum.