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Spatial proximity of Brucella and PrPC during the first steps of infection of the murine macrophage-like cell line J774. Cells cultured on coverglasses were infected as described in Materials and Methods and were analyzed by confocal microscopy. (A to C) B. suis; (D to F) B. abortus; (D, insert) magnification of the contact between B. abortus and PrPC.
