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Neutrophil depletion increases susceptibility to GAS skin infection. (A) H&E staining of excised skin lesions from representative control and depleted Cnlp+/+ mice infected with subcutaneous GAS (inoculum, 4.5 × 105 CFU). Arrows indicate infiltrating leukocytes. Bars, 50 μm. (B) Bacterial counts from excised skin lesions of control and depleted Cnlp+/+ mice infected with GAS (n = 3). Skin lesions were biopsied, homogenized, and plated on TSA to recover GAS.
