FIG. 2.

Levels of LAM-specific IgG induced by primary and secondary intradermal BCG vaccinations. Each vaccination led to a significant increase in LAM-specific antibodies. Panel A shows the individual values for the eight volunteers who received two vaccinations, the first one on day 0 and the second one on day 168. The values for two additional volunteers were excluded because they did not receive the second vaccination on day 168. Panel B shows the mean values of the responses (small squares) and standard errors (bars). *, P < 0.05 by the Tukey HSD test with repeated-measures ANOVA. Arrows indicate the timing of the primary and secondary BCG vaccinations. D0, D56, D112, etc., represent days postvaccination. All serum samples were studied at a serum dilution of 1:50.