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. 2005 Oct;73(10):7014–7017. doi: 10.1128/IAI.73.10.7014-7017.2005

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Copyright © 2005, American Society for Microbiology

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FIG. 2. — Mouse kidney tissue infected with Leptospira. A hematoxylin and eosin stain of a normal C3H/HeJ kidney (A), compared to an infected C3H/HeJ kidney (B) and an infected C3H/SCID kidney (C), is shown (original magnification, ×200). Infected kidneys show evidence of tubular injury. Frankly necrotic renal tubules are indicated by arrows compared to a renal tubule with early necrotic changes (asterisk). The immunohistochemistry of a negative-control kidney (D), compared to an infected C3H/HeJ kidney with granular debris (E) and infected C3H/SCID kidney with intact leptospires (arrows) (F), is shown (original magnification, ×200).