FIG. 4.

Role of NF-κB in regulation of cytokines made in response to P. aeruginosa. WT CFTR-LCFSN or WT CFTR S9 cells were infected with P. aeruginosa strain PAO1 following a 15-min exposure to Bay-11-7082 (SIGMA), an NF-κB inhibitor (gray bars). Black bars represent infected samples not exposed to inhibitor. Results for CXCL1 for WT CFTR-LCFSN and WT CFTR S9 cells are indicated using different scales due to the difference in the quantity of cytokines produced by the different cell lines. Inhibited samples were compared to uninhibited samples of the same cell line using one-tailed unpaired t tests to detect significant decreases. ND, none detected.