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Production of IL-1β, IL-6, and TNF-α by PBMC in response to EF + PA (edema toxin), where PA concentrations are 2.5-fold higher than EF. SEB was not added to these cell cultures. Values are the means ± SD from two PBMC samples and three separate experiments. Results for IL-1β and IL-6 at all concentrations of edema toxin are significantly different (P < 0.05) from the control (0 nM EF) consisting of medium without EF and PA.
