FIG. 1.

Adjuvant effect of FljB on the plasma IgG response to SBR. Mice were immunized by the i.n. route on days 0 and 18 with 20 μg SBR or 20 μg SBR coadministered with 5 μg FljB. Wild-type mice receiving PBS via the i.n. route served as controls. The plasma anti-SBR IgG response was analyzed 2 weeks following the second i.n. immunization (day 32) and on day 70. Results represent the arithmetic mean ± the standard error of the mean (SEM) of eight mice per group. *** indicates significance differences between the groups of mice at P < 0.001.