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(A) Histological section from a nonimmunized rabbit challenged with RDEC-H19A showing intimate bacterial adherence and effacement of microvilli. Bacteria are adhering to the cecal enterocytes, and the mucosal surface has become irregular with a cluster of desquamating cells (white arrow). In comparison, the mucosa from an immunized and challenged animal remained normal (B). Hematoxylin and eosin staining; magnification, ×400.
