TABLE 2.
CFU in nasal washes, nasal tissues, brains, and lungs of mice inoculated i.n.
| Expt | Inoculum
|
No. of mice | Log10 CFU ina:
|
|||||
|---|---|---|---|---|---|---|---|---|
| Strain | Dose (log10) | Nasal wash | Nasal tissue | Olfactory bulbb | Brainb | Lungb | ||
| 1 | TIGR4 | 5.78 | 4 | 3.55 (0.35) | 2.63 (0.06) | 1.0 (0.00)c | <1.0 | 2.66 (0.39) |
| 2 | EF3030 | 7.21 | 3 | 3.98 (0.07) | 6.63 (0.16) | 5.50 (1.60) | 2.68 (0.47) | 2.1 (0.1) |
| 3 | BG7322 | 6.33 | 3 | 3.17 (0.16) | 3.93 (0.08) | 2.37 (0.47) | 1.34 (0.04) | ND |
| 4 | BG7322 | 6.92 | 3 | 4.03 (1.48) | 5.78 (1.88) | 2.53 (0.07) | 1.63 (0.048) | <1.6c |
| 5 | L82016 | 6.69 | 5 | 2.28 (0.23) | 2.27 (0.32) | <1.0 | 1.5 (0.50) | <1.6 |
| 6 | L82016 | 6.66 | 5 | 2.78 (0.30) | 3.81 (0.31) | <1.0 | <1.0 | <1.6 |
| 7 | L82016 | 6.80 | 3 | 4.067 (0.35) | 4.953 (0.10) | 0.55 (0.25) | 0.30 (0.00) | 2.67 (0.07) |
a
Mean (standard error). The values indicate the total numbers of CFU in the tissues.
b
The values for the average numbers of CFU in the olfactory bulb, the remainder of brain, and the lung are averages for positive mice only. ND, not done.
c
<1.0 or <1.6 log10 CFU are the limits of detection. These values are given when there were no colonies in the tissue of any of the inoculated mice.