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Protective capacity of YpTEX-CD40L-transfected trypomastigotes. A group of six mice (▴) that survived after YpTEX-CD40L infection were challenged intraperitoneally at day 55 postinfection (day 0 of reinfection) with a different strain of T. cruzi trypomastigotes (Tehuantepec strain; 100 trypomastigotes). Five mice (control group) (▪) were infected at the same time with the same inoculum. (A) Parasitemia. (B) Cumulative mortality. The data are representative of one of two experiments.
