FIG. 2.

Neutrophils protect against infection with R. equi. Bacterial burdens in the liver, spleen, and lung 7 days after R. equi infection of principal mice rendered neutropenic with RB-8C5 MAb (○) and neutrophil-replete control mice (×). Individual CFU values and the median (horizontal line) values for all surviving principal (n = 7) and control (n = 8) mice are shown. Wilcoxin rank-sum analyses indicated a significant difference (P < 0.05) in median concentrations of R. equi in livers and spleens, between principal and control mice, but not a significant difference in these concentrations in their lungs.