TABLE 4.
Comparison of vibriocidal antibody responses in sera in O139 patients recruited from 1993 to 1995 and in 2002
| Day after onset | Vibriocidala titer (GM)b
|
|||
|---|---|---|---|---|
| 1993-1995 strain
|
2002 strain
|
|||
| 4260B | CIRS134 | 4260B | CIRS134 | |
| 2 | 11 (8-14) | 8 (6-11) | 16 (10-24) | 30 (21-41) |
| 7 | 137 (83-226) | 682 (457-1,018)c | 496 (353-674) | 1,779 (1,236-2,559)c |
| 21 | 54 (28-107) | 103 (48-220) | 370 (262-503) | 692 (501-955) |
a
Vibriocidal responses were studied using strain 4260B (isolated in 1993) utilizing conventional methods (31) or strain CIRS 134 utilizing a modified method as described in the text.
b
GM, geometric mean plus range (±1 SEM).
c
Statistical significance (P < 0.001 [2002]); P < 0.033 [1993 to 1995]) was determined by using the Wilcoxon signed-rank test.