TABLE 6.
Comparison of serum vibriocidal antibody responses in vaccinees challenged with the bivalent cholera toxin B-subunit O1/O139 whole-cell cholera vaccine by using 4260B and CIRS134 as target bacteria
| Parameter | Strain used for vibriocidal assay
|
|
|---|---|---|
| 4260B | CIRS134 | |
| Fold differencea | 1 | 3.0 |
| GMb (range) | 8.5 (6-11) | 59 (39.5-87) |
| Responder frequencyc | 2/21 (9.5) | 10/20 (50) |
a
Postimmunization titer (geometric mean) compared to preimmunization titer.
b
Geometric mean (GM) plus range (±1 SEM) are shown.
c
A ≥4-fold increase in vibriocidal titer between pre- and postimmunization specimen was shown to signify seroconversion.