Table 2.

Univariable and Multivariable Analysis of 90-Day Outcomes and Overall Revisions Among Matched Cohort of +Posterior Lumbar Fusion +Cystic Fibrosis and +Posterior Lumbar Fusion -Cystic Fibrosis

Factor or Variable	Univariable			Multivariable (+PLF+CF compared with +PLF-CF)
	+PLF -CF (1,263)	+PLF +CF (127)	P Value	OR (95% CI)	P Value
90-day outcomes
Any adverse event	325 (25.7%)	53 (41.7%)	0.0002	2.1 (1.5-3.2)	0.0001
Pulmonary	159 (12.6%)	38 (29.9%)	<0.0001	3.1 (2.0-4.8)	<0.0001
Pleural effusion	18 (1.4%)	<11	0.0181	3.4 (1.2-8.5)	0.0111
Dyspnea	92 (7.3%)	25 (19.7%)	<0.0001	3.2 (1.9-5.2)	<0.0001
Respiratory failure	38 (3.0%)	<11	0.0091	2.8 (1.3-5.8)	0.0061
Pneumonia	32 (2.5%)	<11	0.0323	2.6 (1.1-5.7)	0.0200
Atelectasis	50 (4.0%)	<11	0.1511	1.9 (0.8-3.7)	0.1010
Nonpulmonary	238 (18.8%)	31 (24.4%)	0.1629	1.4 (0.9-2.2)	0.1320
VTE	31 (2.5%)	12 (9.4%)	<0.0001	4.2 (2.0-8.1)	<0.0001
AKI	51 (4.0%)	11 (8.7%)	0.0292	2.4 (1.1-4.7)	0.0181
Sepsis	27 (2.1%)	<11	0.1287	2.3 (0.8-5.4)	0.0780
UTI	90 (7.1%)	15 (11.8%)	0.0839	1.8 (0.9-3.1)	0.0608
Transfusion	30 (2.4%)	<11	0.4391	1.7 (0.6-4.1)	0.2994
Cardiac event	15 (1.2%)	<11	1.0000	1.3 (0.2-4.8)	0.7235
Wound complication	49 (3.9%)	<11	0.5394	0.6 (0.1-1.7)	0.3882
Surgical site infection	45 (3.6%)	<11	0.3554	0.4 (0.1-1.4)	0.2501
Readmission	134 (10.6%)	26 (20.5%)	0.0015	2.2 (1.4-3.5)	0.0011
ED visit	235 (18.6%)	40 (31.5%)	0.0008	2.1 (1.4-3.2)	0.0004
Subsequent lumbar surgery (4-yr)	68 (9.5%)	15 (13.3%)	0.2849	1.4 (0.8-2.6)	0.2417

AKI = acute kidney injury, CF = cystic fibrosis, CI = confidence interval, ECL = Elixhauser comorbidity index, ED = emergency department, PLF = posterior lumbar fusion, OR = odds ratio, UTI = urinary tract infection, VTE = venous thromboembolism

Odds ratios represent the odds of 90-day outcomes and any revision surgery among patients who are +PLF+CF compared with +PLF-CF patients.

Bold values indicate the statistical significance set at P < 0.05.