FIG. 1.

Physical maps of intergenic spacer regions between 23S (rrl) and 16S (rrs) rRNA genes of Borrelia hermsii, B. miyamotoi, B. burgdorferi, and B. garinii. Arrows indicate the direction of transcription, and gray or black indicates the strand. The other loci shown are cof (a hydrolase homolog), hpt (hypoxanthine-guanine phosphoribosyltransferase), purA (adenylosuccinate synthetase), purB (adenylosuccinate lyase), mag (methylpurine-DNA glycosylase), ileT (isoleucine tRNA), alaT (alanine tRNA), and ψrrs (a 16S rRNA pseudogene). The IGS sequences for B. burgdorferi B31 and B. garinii PBi are taken from accession numbers NC_001318 and NC_006156, respectively. The rrs pseudogene between alaT and ileT in B. garinii PBi was not previously noted in the annotation of this genome (9).