TABLE 3.

Adherence to and transmigration across the squamous epithelium by wild-type and mutant BC7^a

Strain	Bacteria (% reduction ± SD)
	Adherent	Transmigrated
BC7	0	0
cblA::Tp	89.4* ± 5.37	93.2* ± 10.73
cblS::Tp	94.4* ± 5.70	98.5* ± 10.80
adhA::Tp	98.5* ± 1.45	100.0* ± 0.0
cblS::Tp (pUCP18Tc-cblS)	3.0 ± 2.41	2.9 ± 5.00

^aThe numbers represent the average and standard deviation (SD) from five independent experiments of duplicates or triplicates (n = 10 to 15). For calculation of percent reduction, wild-type BC7 binding to and transmigration across squamous epithelial cell cultures was considered 100%, which was 7.8 × 10³ ± 9.0 × 10² and 6.7 × 10² ± 8.5 × 10¹, respectively. The P values were derived from percentages using ANOVA by modeling the natural log transformation based on two factors: the infection type and the experimental variations. *P < 0.001.