FIG. 6.

E2348/69Δtir mutant strain shows reduced adherence capacity to small intestinal epithelial cells on HPS-stained sections (HPS, arrow), although with a loss of A/E capacity but a close attachment with effacement of the brush border (**) with no evidence of actin polymerization and pedestal formation (arrowheads) on TEM and SEM sections. Inset demonstrates the close attachment with the effacement phenotype observed with E2348/69Δtir on SEM. BB, brush border. Magnifications: HPS, ×40; TEM, ×10,500; SEM, ×8,000.