FIG. 2.
BvfA is required for the virulence of B. suis in the cell infection virulence models. Monolayers of THP1 macrophages (A) and HeLa (B) and J774 (C) cells were infected with 106 CFU of wild-type (filled squares), 1330bvfA::kan B. suis (filled triangles), 1330bvfA::kan with pBBR1-BvfA (open squares), or virB2::Tn5 (filled circles). Data points are geometric means of three wells with the standard error shown. This data set is representative of at least five independent experiments with similar results.