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. 2005 Sep;73(9):5524–5529. doi: 10.1128/IAI.73.9.5524-5529.2005

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Copyright © 2005, American Society for Microbiology

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FIG. 3. — BvfA is required for virulence of B. suis in mice. (Left) Brucella persistence in spleens of mice inoculated with B. suis 1330 wild-type and the 1330bvfA::kan strain. BALB/c mice were inoculated intraperitoneally with 2 × 10⁵ CFU of B. suis 1330 wild types (filled squares) and the 1330bvfA::kan strain (open triangles). Five mice were used for each time point. The number of CFU in spleens was determined at different weeks postinfection (geometric means ± standard deviations of the means). (Right) Spleen weights of mice infected with B. suis 1330 and 1330bvfA::kan at 4 and 8 weeks postinfection. , significantly different from the wild type (P < 0.05).

Inline graphic — BvfA is required for virulence of B. suis in mice. (Left) Brucella persistence in spleens of mice inoculated with B. suis 1330 wild-type and the 1330bvfA::kan strain. BALB/c mice were inoculated intraperitoneally with 2 × 10⁵ CFU of B. suis 1330 wild types (filled squares) and the 1330bvfA::kan strain (open triangles). Five mice were used for each time point. The number of CFU in spleens was determined at different weeks postinfection (geometric means ± standard deviations of the means). (Right) Spleen weights of mice infected with B. suis 1330 and 1330bvfA::kan at 4 and 8 weeks postinfection. , significantly different from the wild type (P < 0.05).