TABLE 1.

Brazilian study subjects^a

Parameter	MB	MB in Rx	PB	HHC	ML+HC	ML−HC	TB
No. of individuals per group	19	13	15	21	13	30	16
Clinical leprosy diagnosis	+	+	+	−	−	−	−
% T-cell response to M. leprae (%)b	0	92	100	62	100	0	31
% Detected with anti-PGL-I IgM	100	69	13	14	0	0	19
% Detected using M. leprae antigenc	0	85	93	62	100	7	50

^aMB, multibacillary; PB, paucibacillary; MB in Rx, leprosy patients with reaction; HHC, healthy household control; ML+HC, healthy endemic controls showing significant T-cell responses to M. leprae extracts; ML-HC, showing no T-cell responses to M. leprae extracts; TB, tuberculosis patients.

^bT-cell responses to M. leprae extracts were considered positive if IFN-γ production levels in response to one or more antigens were >200 pg/ml.

^cT-cell responses to five individual M. leprae antigens (ML0576, ML2283, ML2567, ML1989, and ML1990) were analyzed. Individuals were considered positive if they recognized one or more antigens (>200 pg/ml).