FIG. 2.
Effect of anti-CD4 or anti-CD8 T-cell subpopulation depletion on the resolution of a secondary C. muridarum genital tract infection of IgA+/+ and IgA−/− mice. Following the resolution of primary infection, groups of mice were treated with PBS (nondepleted group) (A), anti-CD8 (B), or anti-CD4 (C) and rechallenged (day 62 after primary infection) with infectious chlamydia (5 × 104 IFUs). Infection was monitored as described in the Fig. 1 legend (9). Data are presented as log10 IFU and represent the means plus standard errors of the means of triplicate determination of five to seven mice per group. No significant differences between IgA+/+ and IgA−/− mice were found (Students t test).