TABLE 1.
Genital tract reinfection of wild-type (IgA+/+) and IgA-deficient (IgA−/−) mice
| Treatmenta | No. of culture-positive mice/total no. of micec on indicated day postchallengeb
|
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IgA+/+
|
IgA−/−
|
|||||||||||
| 3 | 7 | 10 | 14 | 21 | 42 | 3 | 7 | 10 | 14 | 21 | 42 | |
| PBS | 3/6 | 0/6 | 0/6 | 0/6 | 0/6 | 0/6 | 5/5 | 1/5 | 0/5 | 0/5 | 0/5 | 0/5 |
| Anti-CD8 | 4/6 | 1/6 | 0/6 | 0/6 | 0/6 | 0/6 | 1/5 | 3/5 | 0/5 | 0/5 | 0/5 | 0/5 |
| Anti-CD4 | 5/6 | 5/6 | 4/6 | 4/6 | 2/6 | 0/6 | 4/7 | 3/7 | 2/7 | 0/7 | 0/7 | 0/7 |
a
Mice were treated with either PBS, anti-CD8, or anti-CD4 as described in the Fig. 1 legend.
b
Days following secondary infectious challenge.
c
Number of culture-positive mice/total number of mice rechallenged with infectious chlamydiae.