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. 2024 Dec 14;30(7):oyae322. doi: 10.1093/oncolo/oyae322

Table 4.

Summary of AEs by GVS in older (≥70 years old) patients receiving olaparib plus bevacizumab.

AEs GVS = 0
(n = 34)
GVS ≥ 1
(n = 48)
Grade ≥3 21 (61.8) 35 (72.9)
Serious AEs 12 (35.3) 21 (43.8)
Leading to dose interruption 17 (50.0) 32 (66.7)
Leading to dose reduction 12 (35.3) 26 (54.2)
Leading to discontinuation 10 (29.4) 13 (27.1)
Leading to death 0 (0) 0 (0)

Data are n (%) unless otherwise stated. Relationship to the indicated agent was assessed by the investigator. AEs were graded according to the CTCAE, version 4.03.

Abbreviations: AE, adverse event; CTCAE, National Cancer Institute Common Terminology Criteria for Adverse Events; GVS, Geriatric Vulnerability Score.