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. 2005 Sep;73(9):5873–5882. doi: 10.1128/IAI.73.9.5873-5882.2005

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Copyright © 2005, American Society for Microbiology

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FIG. 7. — The vieA(E170A) mutant is attenuated for colonization of the infant mouse. Competition assays were performed with the infant mouse model of cholera. Strains AC-V1596 [vieA(E170A)], AC-V1869 (vpsR::pGP704), and AC-V1870 [vieA(E170A), vpsR::pGP704] were competed against strain O395. Strains AC-V1815 and AC-V1824 [vieA(E170A) containing the pMMB67EH or pAT1822 complementing plasmid, respectively] were competed against strain AC-V1109 (O395 carrying pMMB67EH). The competition index is the ratio of mutant to wild-type bacteria recovered from the small intestine, corrected for the ratio present in the inoculum. Each dot represents an individual mouse; the gray line represents the geometric mean of the data. The competition indices from in vitro competitions in LB are indicated above the graph.