Table 1.

The demographic characteristics and patient details

Study	Treatmentregimen	Numberof patients	Year	Female/male (n)	Study type	Age (mean 6SD) (years)	Race	Follow-up(years)
Tallstedt et al.	Antithyroid drug plus thyroxine65/subtotal thyroidectomy followed by thyroxine 64	65/64	1992	107/22	RCT	Young adults:28±4 old adults: 45±6	Sweden	2
Trgring et al.	Antithyroid drugs plus T4/subtotal thyroidectomy followed by T4	71/67	1996	113/25	RCT	Young adults:29±4 old adults: 45±6	Sweden	2
Ljunggren et al.	Antithyroid drug plus thyroxine/subtotal thyroidetomy followed by thyroxine	68/76	1998	NR	RCT	NR	Sweden	2
Abraham Nordlin et al.	Antithyroid drugs plus/subtotal thyroidectomy followed by thyroxine thyroxine	55/56	2005	NR	RCT	NR	Sweden	1.5
P Laurberg et al.	Antithyroid drugs plus L-thyroxine/ subtotal thyroidectomy followed byL-T4	48/47	2008	NR	RCT	NR	Sweden	2
Ta et al.	Anti-thyroid drugs/subtotal thyroidectomy	28/28	2010	12/72	RCT	35.83±12.01	China	1
Erdoğan et al.	Antithyroid drug /total thyroidectomy	18/24	2016	Total thyroidectomy:7/11 antithyroid drug:12/12	RCT	Total thyroidectomy:44±8.7 antithyroid drug:35±12.9	Britain	3