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. 2002 Jun 24;99(14):9260–9265. doi: 10.1073/pnas.132051799

Figure 3.

Figure 3

Northern blot and in situ hybridization analysis of PRKX. (A) Lanes 1 and 2, 16-week normal fetal human kidney (FHK); lanes 3 and 4, normal adult human kidney (NHK). Arrow, 6-kb PRKX mRNA; arrowhead, 14S rRNA control. (B) Digoxigenin-substituted PRKX antisense riboprobe was hybridized to human fetal kidney sections and visualized by antidigoxigenin-alkaline phosphatase immunohistochemical staining. (A) Fetal human kidney at 12 weeks gestation showing ureteric bud PRKX expression (arrowhead). (B) Normal human adult kidney cortex (female). (C) Early-stage ADPKD kidney showing PRKX expression in cyst epithelial cells.