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In vitro response to TNF. (a) Sensitivity of MEFs from C57BL/6, (B × S)F1, and M. spretus. The absorbance of untreated cultures was regarded as 100%. (b) IL-6 induction on primary macrophages. White bars, C57BL/6; hatched bars, (B × S)F1; black bars, M. spretus. ***, P < 0.0001 compared with C57BL/6 mice. Data are representative of three independent experiments.
